Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure (HEMOSTIR)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Hemorrhage; Coagulation Disorder; Acute Renal Failure

Study type: Observational

Funder types: Other

Identifiers

NCT03536195

HEMOSTIR (29BRC17.0132)

Details and patient eligibility

About

Renal failure and high plasmatic level of urea have been associated with an increased risk of hemorrhage in surgical patients. There is only sparse data on the impact of renal replacement therapy on homeostatic parameters. The aim of this study is to describe potential changes in homeostatic parameters before and after renal replacement therapy.

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• critically ill patients
• acute renal failure
• renal replacement therapy
• plasmatic urea > 20

Exclusion criteria

• chronic renal failure
• platelet count less than 80 Giga
• V factor less than 70%