Impact of Rheumatoid Arthritis on the Course of Type 2 Diabetes During a Longitudinal Follow-up of 5 Years (INSPIRED)

Assistance Publique - Hôpitaux de Paris

Status: Terminated

Conditions: Type 2 Diabetes

Study type: Observational

Funder types: Other

Identifiers

NCT02639988

NI15005

Details and patient eligibility

About

The purpose of this study is to determine whether patients with rheumatoid arthritis and type 2 diabetes experience a more severe disease course compared to control patients with osteoarthritis and type 2 diabetes

Enrollment: 176 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients

• Adults (>18 years)
• Rheumatoid arthritis fulfilling American College of Rheumatology (ACR )1987 or European League Against Rheumatism (ACR/EULAR) 2010 classification criteria
• Type 2 diabetes (HbA1c ≥6.5% OR fasting glycemia≥7 mmol/l OR glycemia 120 min after 75 mg glucose ingestion ≥ 11.1 mmol/l OR symptoms of hyperglycemia with glycemia ≥11.1 mmol/l)
• Affiliated to social security system

Controls

• Adults (>18 years) matched for age, sex and BMI with patients with rheumatoid arthritis
• Osteoarthritis (knee, hip, spine and hand)
• Type 2 diabetes with disease duration matched with patients with rheumatoid arthritis
• Affiliated to social security system

Exclusion criteria

• Patient not able to understand study implication and rules
• Patient opposed to participate to the study
• Transient diabetes
• Gestational diabetes
• Secondary diabetes

Trial design

176 participants in 2 patient groups

rheumatoid arthritis and type 2 diabetes

osteoarthritis and type 2 diabetes