Impact of Sarpogrelate in the Function of Endothelial Progenitor Cells

Aichi Gakuin University

Status: Unknown

Conditions: Atherosclerosis

Treatments: Drug: Sarpogrelate

Study type: Interventional

Funder types: Other

Identifiers

NCT01548274

AGU-65

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of Sarpogrelate in endothelial progenitor cells of patients with atherosclerosis.

Full description

Endothelial progenitor cells play an important role in vasculogenesis and vascular repair. Sarpogrelate, a inhibitor of HT2A, is used an an anti-platelet drug, however, a direct effect in vascular cells is supposed.

Enrollment: 20 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with atherosclerosis

Exclusion criteria

• Patients with high risk of bleeding
• Patients with pregnancy
• Patients with allergic reaction of Salpogrelate

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)