Impact of Screen Size on Colorectal Adenoma Detection

The Chinese University of Hong Kong

Status

Unknown

Conditions

Colon Adenoma

Colorectal Neoplasms

Colon Polyp

Treatments

Procedure: Large Screen

Study type

Interventional

Funder types

Other

Identifiers

NCT04749303

2020.327

Details and patient eligibility

About

The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.

Full description

Colorectal cancer is the 3rd most common cancer in the world. Recently in Hong Kong it has surpassed lung cancer to be the most common cancer. Hence it is essential not only to have up-to-date surgical and oncological treatment but also a need an effective preventative strategy.

In the past few decades, removal of pre-malignant colonic lesions such as adenomas have been shown to prevent development of colorectal cancers. Colonoscopy is currently the only technique which can perform both detection and treatment during the same procedure. However, concerns have been raised about the effectiveness of colonoscopy in the prevention of CRC after several studies reported unexpected high incidence rates of interval carcinomas (IC), especially in the proximal colon. Most ICs are suspected to arise from missed colon lesions during colonoscopy. Factors concerning missed colonic lesions are multifactorial such as adequate bowel preparation, skill level of endoscopists, the number of endoscopy staff in the room as "eyes" to help with polyp detection and withdrawal time.

Following a pilot study in our endoscopy unit, we believe the size of the screen projecting the endoscopic image may have a positive influence on adenoma detection. Therefore, we feel that a well-designed and adequately powered randomised controlled trial may help to confirm this.

Enrollment

656 estimated patients

Sex

All

Ages

18 to 99 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients aged 18 years or above
Referred to the endoscopy unit for diagnostic or surveillance colonoscopy

Exclusion criteria

Familial history of Familial adenomatous polyposis or Hereditary non-polyposis colorectal cancer
Known history of inflammatory bowel disease
Emergency endoscopy of any nature (such as for gastrointestinal bleeding, assessment of large bowel investigation and colonic decompression)
Patients with colostomy
Previously incomplete colonoscopy (not including insufficient preparation)
Patients with known palliative colorectal malignant disease Patients with coagulopathies Inability to give informed consent