Impact of Sinus Surgery on Individuals With Cystic Fibrosis

University of California, Los Angeles (UCLA) logo

University of California, Los Angeles (UCLA)

Status

Enrolling

Conditions

Cystic Fibrosis
Chronic Rhinosinusitis (Diagnosis)

Study type

Observational

Funder types

Other

Identifiers

NCT04469439
20-002079

Details and patient eligibility

About

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

Enrollment

170 estimated patients

Sex

All

Ages

18 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old). Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines chronic rhinosinusitis symptoms persisting beyond initial medical treatment Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment

Exclusion criteria

Underwent endoscopic sinus surgery in past 12 months Will obtain follow up care at non-participating institutions Unable to complete follow-up surveys

Trial design

170 participants in 2 patient groups

Surgical group
Description:
Individuals with cystic fibrosis and chronic rhinosinusitis who undergo endoscopic sinus surgery
Medical group
Description:
Individuals with cystic fibrosis and chronic rhinosinusitis who do not undergo endoscopic sinus surgery

Trial contacts and locations

1

Loading...

Central trial contact

Karolin Markarian, BS; Daniel M Beswick, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems