Impact of Standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke (MonDAFIS)

Charité University Medicine Berlin

Status

Completed

Conditions

Atrial Fibrillation

Stroke

Treatments

Device: ECG

Other: prolonged ECG monitoring

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT02204267

MonDAFIS

EA2/033/14

Details and patient eligibility

About

Investigator-initiated prospective randomized multicentre study to uncover the true burden of paroxysmal atrial fibrillation in a representative population of acute stroke patients without known atrial fibrillation.

Enrollment

3,470 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Acute ischemic stroke or transitory ischemic attack (with clinical deficit on enrolment or MRI detected acute brain lesion on admission)
Age ≥ 18 years
Written or oral informed consent
Stroke unit admission within 72 hours after stroke onset
Start of standardized prolonged ECG monitoring within 24 hours after admission to the stroke unit
Willingness to take part in the planned follow up examinations

Exclusion criteria

Known atrial fibrillation
Atrial fibrillation detected by ECG on admission
Atrial fibrillation detected prior study enrollment on the stroke unit
Life expectancy < 1 year (before actual stroke)
Life expectancy < 1 month (after actual stroke)
Indication for oral anticoagulation other than atrial fibrillation (e.g. mechanical heart valve)
Severity level according National Institute of Health Stroke Scale (NIHSS) score > 22
Participation in an interventional trial