Impact of Steroid, Diuretic, and Fluid Use on BPD Outcomes

Pediatrix

Status: Completed

Conditions: BPD - Bronchopulmonary Dysplasia

Treatments: Other: No interventions or procedures

Study type: Observational

Funder types: Other

Identifiers

NCT04971694

830900795

Details and patient eligibility

About

Assess the impact of steroid, diuretic, and fluid practices on BPD outcomes in extreme premature infants in the Banner - University Medical Center Phoenix (BUMCP) neonatal intensive care unit (NICU).

Full description

The investigators propose performing a retrospective analysis of the current respiratory management methods to potentially find a correlation between the number of steroid doses administered, the timing of initiation of steroid therapy and the effect on premature infants at risk for developing BPD. The investigators are also going to explore the number and timing of diuretic medications and average fluid intake.

Enrollment: 175 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants born at <30 weeks and/or <1500g
• Admitted to BUMCP between January 1, 2019 and December 31, 2020

Exclusion criteria

• Infants that do not survive to 36 weeks CGA, when the determination of BPD is made
• Infants that are transferred to another hospital prior to 36 weeks CGA
• Out born infants
• Infants with life threatening congenital anomalies
• Investigator discretion as to other factors which might impact the study

Trial design

175 participants in 1 patient group

Inclusion Group

Description:

Infants born at \<30 weeks and/or \<1500g that were admitted to BUMCP between January 1, 2019 and December 31, 2020

Treatment:

Other: No interventions or procedures