Impact of TAVI on Cognition, Mood and Health-related Quality of Life

Medical University of Graz

Status

Not yet enrolling

Conditions

Cognitive Impairment

Treatments

Other: cognitive research battery, MRI, laboratory values

Study type

Observational

Funder types

Other

Identifiers

NCT04371172

32-249 ex19/20 (Other Identifier)

32-249 ex 19/20

Details and patient eligibility

About

In the proposed study, patients with and without embolic protection devices during Transcatheter Aortic Valve Implantation will be repeatedly examined with a comprehensive psychiatric and cognitive test battery over a post-interventional period of 6 months after TAVI, with regard to the effects on mood, cognitive Performance and health-related Quality of life.

Full description

The percutaneous aortic valve replacement (TAVI, Transcatheter Aortic Valve Implantation) enables the implantation of a new biological aortic valve at the beating heart. The procedure is performed under local anaesthesia and is a gold standard in the therapy of aortic stenosis, especially in patients with a too high health risk for cardiovascular surgery.

In the proposed study, patients with and without embolic protection devices during TAVI will be repeatedly examined with a comprehensive psychiatric and cognitive test battery over a post-interventional period of 6 months after TAVI, with regard to the effects on mood, cognitive Performance and health-related quality of life.

Enrollment

128 estimated patients

Sex

All

Ages

19 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Written declaration of consent of the study participants to participate in the study after detailed information on the nature, significance, risks and scope of the study.
Women and men between the ages of 19 and 90
Clinical indication for TAVI intervention
No previous psychiatric illness before TAVI
No other serious disease affecting the immune system

Exclusion criteria