Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia (SONG)

Centre Hospitalier le Mans

Status: Not yet enrolling

Conditions: Intubated Patient Requiring a Gastric Tube

Treatments: Other: nasogastric tube and orogastric tube; Other: orogastric tube and nasogastric tube

Study type: Interventional

Funder types: Other

Identifiers

NCT05915663

CHM-2022/S03/05

Details and patient eligibility

About

In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube. In some cases, the tube is inserted through the nose and in others, it is inserted through the mouth.

In the literature and in practice, these gastric tubes create discomfort and complications that have an impact not only on the patient, but also on the treatments and the length of the patient's stay in hospital.

Nosocomial Ventilator Associated Pneumonia is the most serious common complication for patients intubated with a gastric tube. It is possible that placement site may have an impact on the risk of developing Ventilator Associated Pneumonia, particularly by increasing the risk of bacterial pullulation opposite the sinuses when the tube is placed via the nasal route.

Investigator hypothesises that placing the gastric tube orally will reduce the rate of ventilator-associated pneumonia compared with the nasal route in mechanically ventilated intensive care patients.

Enrollment: 2,400 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient in intensive care, intubated, ventilated
• Adult
• Requiring a gastric tube
• With an expected duration of mechanical ventilation of more than 48 hours
• Affiliated to social security
• Patient or relative consent or, failing that, emergency inclusion of the patient

Exclusion criteria

• Pregnant, breast-feeding or parturient women
• Patients under legal protection: curatorship and guardianship
• Contraindication to placing a gastric tube through the nose or mouth
• Patients who already have a gastric tube when they enter the service
• Patient intubated for more than 24 hours
• Patient intubated via the nasotracheal route

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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2,400 participants in 2 patient groups

Nasogastric

Experimental group

Description:

nasogastric tube in period 1 and orogastric tube in period 2

Treatment:

Other: nasogastric tube and orogastric tube

Orogastric

Experimental group

Description:

orogastric tube in period 1 and nasogastric tube in period 2

Treatment:

Other: orogastric tube and nasogastric tube