Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain

Maisonneuve-Rosemont Hospital

Status: Terminated

Conditions: Complex Regional Pain Syndromes

Treatments: Procedure: Ultrasound-guided technique; Procedure: Blind technique

Study type: Interventional

Funder types: Other

Identifiers

NCT01954888

13054

Details and patient eligibility

About

The first purpose of this study is to compare the effectiveness of the stellate ganglion block realized with two different approaches (blind and ultrasound-guided) in patients with a diagnosis of complex regional pain syndrome.

The second purpose of this study is to determine the safest approach and to compare the safety profiles of the two approaches.

Full description

To evaluate whether the ultrasound guided approach is more effective than the blind technique in producing a greater than 1.5 degree Celsius rise in ipsilateral arm temperature after a stellate ganglion block.

Blocks will both be performed with 10 mL of xylocaine/bupivacaine. Secondary outcomes will be the impact of the approach (blind vs ultrasound) on pain reduction, horner syndrome, side effects (hoarseness, dysphagia, pharyngeal discomfort) and complications (blood aspiration, intravascular injection).

Enrollment: 3 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18 to 80 years
• Patients with a new or known diagnosis of complex regional pain syndrome (according to the criteria of Budapest) at the upper extremity

Exclusion criteria

• Refusal of a patient
• Coagulopathy
• Systemic infection or local infection at the needle injection site
• Major deformation at the level of the neck (radiotherapy, surgery, etc. )
• Concomitant chronic pain syndrome
• Post-pneumonectomy on the controlateral side
• Severe hepatic impairment or severe renal impairment (Clcr under 30 ml/min)
• Known allergy to local anesthetics of amide type
• Inability to understand a numeric pain scale

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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3 participants in 2 patient groups

Blind technique

Active Comparator group

Description:

Stellate ganglion block using the anterior paratracheal approach using surface landmarks.

Treatment:

Procedure: Blind technique

Ultrasound-guided technique

Active Comparator group

Description:

Stellate ganglion block using the ultrasound-guided lateral approach at the sixth cervical vertebral level.

Treatment:

Procedure: Ultrasound-guided technique