Impact Of Thyroid Dysfunction on Liver Function Tests

Sohag University

Status: Enrolling

Conditions: Thyroid Disease

Treatments: Other: Patients with hypothyroidism or hyperthyroidism that are controlled on treatment; Other: Control group; Other: Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment; Other: Patients with hypothyroidism or hyperthyroidism that are firstly discovered

Study type: Observational

Funder types: Other

Identifiers

NCT07354048

Soh-Med--25-7-9MS

Details and patient eligibility

About

This study aims to evaluate the effect of thyroid dysfunction on liver function tests.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients between the ages of 20-60 years old either with Hypothyroidism or Hyperthyroidism (controlled on treatment or not) and firstly diagnosed Hypothyroidism or Hyperthyroidism.
• Euthyroid controls (clinically healthy control subjects were recruited from the general population with the same socio-economic status with the subjects.)

Exclusion criteria

• Patients aged < 20 years old.
• Patients With Liver Disease.
• Pregnant and lactating women.
• Patients with severe infections or sepsis.
• Patients with Heart Disease.
• Patients who on drugs that can affect liver function such as phenothiazine, phenylbutazone, methyldopa, among others.

Trial design

100 participants in 4 patient groups

Control group

Treatment:

Other: Control group

Patients with hypothyroidism or hyperthyroidism that are controlled on treatment

Treatment:

Other: Patients with hypothyroidism or hyperthyroidism that are controlled on treatment

Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment

Treatment:

Other: Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment

Patients with hypothyroidism or hyperthyroidism that are firstly discovered

Treatment:

Other: Patients with hypothyroidism or hyperthyroidism that are firstly discovered