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Impact of Tooth Loss and Denture on Oral Senses and Food Preferences (AlimaPAC)

A

Assistance Publique - Hôpitaux de Paris

Status

Enrolling

Conditions

Tooth-loss

Treatments

Procedure: Tooth removal and their replacement by means of a denture

Study type

Interventional

Funder types

Other

Identifiers

NCT04281056
APHP190340

Details and patient eligibility

About

Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

Full description

Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 79 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls:

controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

Exclusion criteria

  • Aged under 18 or over 80 Y,
  • not consenting to participate
  • suffering from dental
  • periodontal or gum pain for the last month.

Trial design

Primary purpose

Basic Science

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

40 participants in 2 patient groups

Control
No Intervention group
Tooth removal
Experimental group
Description:
Tooth removal and their replacement by means of a denture Teeth have been removed and replaced by means of dentures for at least one year
Treatment:
Procedure: Tooth removal and their replacement by means of a denture

Trial contacts and locations

1

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Central trial contact

Yves Boucher, Professor; Adeline Braud, Doctor

Data sourced from clinicaltrials.gov

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