Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic

Mansoura University

Status: Completed

Conditions: Covid19

Treatments: Diagnostic Test: ELISA; Drug: Vitamin D

Study type: Observational

Funder types: Other

Identifiers

NCT04709744

RP.21.01.91

Details and patient eligibility

About

Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of prior chloroquine on COVID-19 disease outcomes Patients and methods 38 SLE patients previously diagnosed and on different lines of lupus management. Participants were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Serum vit D was measured in serum by ELISA.

Full description

Primary objective: assess the impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection and pandemic treatment outcome.

Secondary objectives:

• Effect of serum vit D level in SLE patients on duration of COVID-19 disease course and fatigue development as a complication for both SLE and COVID-19
• Impact of prior chloroquine on COVID-19 disease outcomes
• Correlation of serum vit D level with different laboratory investigations at time of COVID-19 outbreak

Enrollment: 38 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • SLE patients previously diagnosed
• Patients are not suffering from malignancies.
• Patients have no organ failure nor uncontrolled medical illness.
• Recent COVID-19 infection

Exclusion criteria

• • Pregnant, lactating females
• Concurrent malignancies
• Patients with other autoimmune disease

Trial design

38 participants in 1 patient group

SLE patients

Description:

SLE patients were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Vit D was measured in serum by ELISA. Vit D was added to anti COVID-19.

Treatment:

Diagnostic Test: ELISA

Drug: Vitamin D