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Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD

S

St George's, University of London

Status and phase

Completed
Phase 3

Conditions

CKd Patients With Stage 3 and 4

Treatments

Drug: Cholecalciferol

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Vitamin D deficiency is common in CKD and assciated with CV complications. Endothelial dysfucntion is common in CKD and is a harbinger of atherosclerosis. The study investigated the impact of Vitamin D on endothelial fucntion and blood biomarkers in CKD.

Enrollment

36 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • CKD 3-4 Age 18-80

Exclusion criteria

  • Recent MI, CVA, malignancy active infection active inflammation High calcium already on Viatmin D therapy

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

36 participants in 1 patient group

Vitamin D
Experimental group
Description:
Cholecalciferol 300,000 twice
Treatment:
Drug: Cholecalciferol

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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