Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts (IYOGHRT)

University of Illinois at Urbana-Champaign

Status

Completed

Conditions

Cognition - Other

Physiological Stress

Gastrointestinal Dysfunction

Treatments

Dietary Supplement: Yogurt with B. lactis and added cane sugar

Study type

Interventional

Funder types

Other

Identifiers

NCT04901390

20665

Details and patient eligibility

About

This study aims to test the central hypothesis that adding to the diet daily yogurt provides beneficial effects on digestive health and subjective mood in healthy adults.

Full description

This clinical trial will include a 4-week lead-in period and a 2-week treatment period. The lead-in period will be devoid of all supplemental and dietary probiotics, fermented dairy products, and fermented foods. Participants will be asked to refrain from consuming all supplemental and dietary probiotics, fermented dairy products, and fermented foods throughout the entire study. During the treatment period, participants will be given yogurt with sugar. This trial will serve as a continuation of the NECTAR Study (NCT04187950).

Enrollment

66 patients

Sex

All

Ages

22 to 64 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Males and females
Between the ages of 22-64 years at the time of consent
Body mass index of 18.5 to 29.9 kg/m^2.
Normal or corrected-to-normal vision based on the minimal 20/20 standard in order to complete the cognitive task (below 20/20 vision).
Ability to drop off fecal sample within 30 minutes of defecation
Have between 3-6 bowel movements per week
Have completed the NECTAR Study (NCT04187950)

Exclusion criteria

Current pregnancy, lactation, or post-menopausal
Tobacco use
Honey allergy or intolerance
Dairy allergy, lactose intolerance
Food dye allergy/intolerance
Prior physician diagnosed gastrointestinal disease (chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers, hepatitis, or gastroesophageal reflux disease (GERD))
Current use or use of antibiotics in the past 3 months
Current use of any of the following types of medications: laxatives, anti-diarrhea medications, narcotics, enemas, antispasmodics, anticonvulsants, prescription proton pump inhibitors, prokinetic agents, histamine-2 Rc antagonists (prescription GERD medication)
Body mass index > 29.9 kg/m^2
Prior malabsorptive bariatric surgery (i.e. gastric bypass, sleeve gastrectomy)
Restrictive bariatric surgery (i.e. adjustable gastric band) within the past 5 years
Concurrent enrollment in another dietary, exercise, or medication study (except for the NECTAR Study (NCT04187950))