Impacts of Superselective Infarct-related Artery (IRA) Infusion of Tirofiban on Myocardial Reperfusion and Bleeding Complications in Acute Myocardial Infarction (AMI) Patients (SUIT-AMI)

Capital Medical University

Status: Unknown

Conditions: Myocardial Infarction

Treatments: Procedure: administration of tirofiban by guide catheter; Procedure: administration of tirofiban by thrombus aspiration catheter in infarct-related artery

Study type: Interventional

Funder types: Other

Identifiers

NCT01181388

64456541

Details and patient eligibility

About

Superselective IRA infusion of tirofiban may improve myocardial reperfusion and reduce bleeding complications in AMI patients.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• STEMI patients
• chest pain for less than 12hr
• plan to PCI

Exclusion criteria

• LM lesion
• stent thrombosis
• cardiac shock
• thrombocytopenia
• allergy to asprin

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

intra-guide-catheter infusion of tirofiban

Active Comparator group

Treatment:

Procedure: administration of tirofiban by guide catheter

intra-thrombus-aspiration-catheter infusion of tirofiban

Experimental group

Treatment:

Procedure: administration of tirofiban by thrombus aspiration catheter in infarct-related artery