Impaired Regulation of Energy Balance in Elderly People (Balance Study)

Wageningen University

Status: Completed

Conditions: Anorexia of Ageing

Treatments: Other: Energy restriction period

Study type: Interventional

Funder types: Other

Identifiers

NCT00561145

NL 17278.081.07

Details and patient eligibility

About

Over the past century life expectancy has risen rapidly. As a result, the proportion of elderly people continues to grow. Elderly people probably have an impaired regulation of energy balance (energy intake versus energy expenditure) whereby the underlying physiological mechanisms are not fully understood.

The first objective of this study is to provide further evidence for an age-related failure to regulate energy balance in elderly. If the hypothesis of impaired regulation of energy balance in elderly is confirmed then the second objective becomes to elucidate the underlying physiological mechanisms of the age-related failure to regulate energy intake in elderly.

Enrollment: 32 patients

Sex: Male

Ages: 20 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• men
• healthy
• 20-40 and 65-85 years of age
• normal weight
• free-living in Wageningen and surrounding

Exclusion criteria

• anemia
• diabetes
• restrained eating
• dementia
• weight changes of > 2 kg during the last 2 months

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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32 participants in 2 patient groups

Young men

Experimental group

Description:

Energy restriction period

Treatment:

Other: Energy restriction period

Elderly men

Experimental group

Description:

Energy restriction period

Treatment:

Other: Energy restriction period