Impairment of Sleep and Pattern of Breathing Before and After Opioid Withdrawal in Comparison to Patients Without Opioid Withdrawal

Ruhr University of Bochum

Status: Completed

Conditions: Sleep Architecture Under Opioid Medication

Study type: Observational

Funder types: Other

Identifiers

NCT01540890

Polysom2012

Details and patient eligibility

About

Main of the study is to assess the influence of high-dose opioids on the sleep architecture and patterns of breathing using non-invasive polysomnographic measurements before and after opioid withdrawal in patient who undergo opioid withdrawal independently from the present study. These data will be compared to polysomnographic data of patients under opioid treatment who do not undergo opioid withdrawal as well as to patients without opioid treatment.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• older than 18 year, indication for opioid withdrawal (cohort 1), opioid intake (cohort 1 and 2)

Exclusion criteria

• plaster allergic reactions, opioid withdrawal (cohort 2), opioid intake (cohort 3)

Trial design

40 participants in 3 patient groups

withdrawal

Description:

patients who undergo an opioid withdrawal

opioids

Description:

patients on opioid medication without withdrawal

opioid-free

Description:

patients with chronic pain without opioid medication