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Impedance Spectroscopy in Esophageal Cancer

S

Sana Klinikum Offenbach

Status

Completed

Conditions

Cancer of Esophagus

Treatments

Device: impedance

Study type

Interventional

Funder types

Other

Identifiers

NCT04046601
Barrett08/2019

Details and patient eligibility

About

Detection of early esophageal cancer in surrounding normal tissue can be challenging even for experienced examiners. The early detection is essential to determine the following treatment. Early stages of esophageal cancers can be treated by endoscopic resection whereas advanced neoplasia might lead to an Operation of the esophagus. Diagnosis is made usually by biopsies of suspicious lesions or untargeted quadrant biopsies. The electrical properties in inflammatory tissue and cancer can be sensed by electrical bioimpedance technique.

The aim of this study is to compare the impedance probe with the histological result and to investigate the feasibility of the new technique in detection of esophageal cancer.

Full description

Detection of early esophageal cancer in surrounding normal tissue can be challenging even for experienced examiners. The early detection is essential to determine the following treatment. Early stages of esophageal cancers can be treated by endoscopic resection (ER) whereas advanced neoplasia might lead to esophagectomy. Diagnosis is made usually by biopsies of suspicious lesions or untargeted quadrant biopsies. The electrical properties in inflammatory tissue and dysplasia can be sensed by electrical bioimpedance technique. The aim of this study is to compare the impedance probe with the histological result and to investigate the feasibility of the new technique in detection of esophageal cancer.

Enrollment

67 patients

Sex

All

Ages

18 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Known esophageal cancer and planned for endoscopic resection

Exclusion criteria

  1. Missing consent / agreement
  2. Patient in bad condition for endoscopy or endoscopic resection
  3. Patients with coagulopathy or anticoagulative medication which is a contraindication for endoscopy

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

67 participants in 1 patient group

Impedance
Experimental group
Description:
every resected tissue will measured by an impedance probe
Treatment:
Device: impedance

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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