Implementation of a Personalized Medicine (Pharmacogenomics) Service in a Community Pharmacy

University of North Carolina (UNC)

Status and phase: Completed; Phase 1

Conditions: Stroke; Transient Ischemic Attack; Myocardial Infarction

Treatments: Other: Pharmacogenomics testing for clopidogrel responsiveness

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01495845

10-1558

Details and patient eligibility

About

The purpose of this study is to determine the feasibility of pharmacogenomics testing in a community pharmacy using clopidogrel as an example. The investigators hypothesize that this testing is feasible in this setting.

Full description

To determine if the study is feasible, we will examine the change in patient perception of pharmacogenomics testing (before and after the study), the percentage of patients interested in this service, the response rate of providers to pharmacist recommendations, the pharmacist time requirement, and reimbursement rate for pharmacist services.

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Prescribed clopidogrel (Plavix) by their prescriber
• Aged 18 or older
• Currently on clopidogrel therapy for one of the following indicated uses: post-ACS, Recent PCI with stenting, History of TIA or stroke

Exclusion criteria

• Are unable to complete study materials (surveys) with or without assistance, including non-English speaking patients
• Are taking clopidogrel for a reason other than stated in inclusion criteria
• Are pregnant or nursing
• Have an allergy to aspirin