Implementation of Optical Diagnosis of Diminutive Colorectal Polyps: DISCARD3 Study (Incorporating AI-DETECT)

London North West Healthcare NHS Trust

Status

Completed

Conditions

Colonic Polyp

Treatments

Diagnostic Test: CAD polyp-detection system

Study type

Interventional

Funder types

Other

Identifiers

NCT04710693

245862

Details and patient eligibility

About

This is a prospective feasibility study. The aim of this work is to assess the acceptability and feasibility of optical diagnosis-led care in bowel cancer screening patients undergoing colonoscopy. This study will determine whether bowel cancer screening colonoscopists are able to consistently record and diagnose diminutive adenomas suitable for a resect and discard strategy allowing assignment of surveillance intervals according to Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) criteria. A practical quality assurance program around optical diagnosis will be introduced. The use of a CAD polyp-detection system will also be evaluated (AI-DETECT).

Enrollment

614 patients

Sex

All

Ages

55 to 74 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients aged 60-74
- with +ve Faecal Occult Blood/Faecal Immunochemical test attending for screening colonoscopy within BCSP (Bowel Cancer Screening Programme)
- with an established history of adenomas attending for surveillance colonoscopy within BCSP
Patients aged 55 - referred for screening colonoscopy following positive Bowel Scope Screening flexible sigmoidoscopy

Exclusion criteria

Patients with a risk profile (due to family history or other) whose follow-up will be outside standard BCSP
Patients with inflammatory bowel disease
Unable to consent
Pregnancy