Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit (TRIP)

Stanford University

Status: Invitation-only

Conditions: Red Blood Cell Transfusions

Treatments: Other: Implementation strategies to increase use of transfusion recommendations

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT07108374

HS029298-03 (Other Grant/Funding Number)

70193

Details and patient eligibility

About

Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and death. Recommendations have been developed to restrict transfusion in patients who are unlikely to benefit; however, these recommendations have not been consistently adopted into clinical practice. This study examines use of targeted efforts (implementation strategies) to improve implementation of the recommendations, with a goal of reducing unnecessary transfusions and improving patient outcomes in critically ill children.

Enrollment: 200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Employed at Lucile Packard Children's Hospital at Stanford University or the Children's Hospital of Philadelphia AND
• Employed in one of the following roles:
• PICU nurse
• PICU attending
• PICU fellow
• PICU resident
• PICU advanced practice provider
• Other physician or surgeon in subspecialties whose patients regularly receive transfusions in the PICU
• PICU TRIP implementation team member
• PICU nursing leader
• PICU physician leader
• Bood bank leader.

Exclusion criteria

• Unwilling to participate
• Directly report to the primary investigator.

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)