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Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository (PPS)

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Duke University

Status

Completed

Conditions

Aging
Fitness
Physical Functioning
Cognitive Functioning

Treatments

Genetic: Biomarker studies

Study type

Observational

Funder types

Other

Identifiers

NCT01720472
Pro00036608

Details and patient eligibility

About

The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physical and cognitive performance data paired with biological samples.

Full description

The MURDOCK Study, proposes this Horizon 2 study to collect a brief physical and cognitive performance assessment from 1,000 MURDOCK Registry participants. Blood sample aliquots will also be obtained. These physical and cognitive performance data, paired with -omics data from plasma and serum sample analyses, offer promise in the discovery of biomarkers for functional decline. This research will provide an important basis for our understanding of the physical, lifestyle, and genetic factors which, over the lifespan, contribute to changes in physical and cognitive capabilities as we age.

Enrollment

1,000 patients

Sex

All

Ages

30+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) or certain portions of Rowan, Mecklenburg, or Stanly counties in North Carolina for 6 or more months of the year.
  • Age 30 or older

Exclusion criteria

  • Female that is currently pregnant
  • Having had a heart attack, angina, congestive heart failure, or fluid in the lungs within the past 6 months
  • Participant that requires consent by a legally authorized representative
  • Participant that cannot walk 30ft without human assistance

Trial design

1,000 participants in 1 patient group

Community, Physical Performance
Treatment:
Genetic: Biomarker studies

Trial contacts and locations

6

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Data sourced from clinicaltrials.gov

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