Implementing HPV DNA Self-Collection to Increase Rates of Cervical Cancer Screening in Transgender Men

Augusta University

Status: Unknown

Conditions: Human Papilloma Virus; Cervical Cancer; Transgenderism

Treatments: Diagnostic Test: HPV testing

Study type: Interventional

Funder types: Other

Identifiers

NCT04154358

1410051-2

Details and patient eligibility

About

Transgender men are individuals born genetically female that have a gender identity that is incongruent with their biological sex. For those who have begun or completed transition, they may present as males but still have a uterus and cervix. Thus far, no distinction has been made between routine cervical cancer screening guidelines in non-transgender women and those for transgender men, despite wide variations in sexual practices, including lifelong vaginal abstinence. The purpose of this study is to offer transgender men seen at clinic visits self-collected HPV testing to evaluate for improved cervical cancer screening rates, as well as a survey to further investigate sexual practices, rates of appropriate screening prior to being offered self-collection, and barriers to obtaining appropriate care.

Enrollment: 100 estimated patients

Sex: Female

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age >21 for survey and age> 25 for HPV testing
• Transgender male or gender non-conforming identity
• Female sex at birth
• Consent to participate in the study

Exclusion criteria

• impaired decision making capacity
• Absence of cervix
• Non-English speaking

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

HPV Testing

Experimental group

Description:

Will perform HPV testing with self-collected specimen

Treatment:

Diagnostic Test: HPV testing