Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use

University of Michigan

Status: Active, not recruiting

Conditions: Venous Thromboembolism; Pulmonary Embolism; Atrial Fibrillation

Treatments: Behavioral: Existing-prescription notification to prescriber; Behavioral: New-prescription Alert; Behavioral: New-prescription Alert with referral option; Behavioral: Existing-prescription notification to pharmacist

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT05351749

HUM00207165

R18HS028562 (U.S. AHRQ Grant/Contract)

Details and patient eligibility

About

The researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers. Furthermore, the researchers hypothesize that the availability of a pharmacist referral option is associated with a higher rate of prescription changes for initial-prescription alerts that are directed to the prescriber at the time of initial-prescribing errors.

Findings from this project will establish a framework for implementing prescriber-pharmacist collaboration for high risk medications, including anticoagulants

Full description

Please note that the 3rd and 4th outcome measures are conditional on the outcomes of the 1st and 2nd outcome measures respectively.

Please note that enrollment of 300 will provide sufficient power to study.

Enrollment: 306 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Prescribers:

Inclusion Criteria:

• Michigan Medicine provider with prescribing privileges
• Providers in ambulatory care settings
• Prescribe DOAC to patients 18 years and older

Exclusion Criteria:

• Providers in inpatient settings
• Providers who are members of the study team

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

---

306 participants in 4 patient groups

New-prescription Alert / Existing-prescription notification to prescriber

Experimental group

Treatment:

Behavioral: New-prescription Alert

Behavioral: Existing-prescription notification to prescriber

New-prescription Alert w/ referral option/ Existing-prescription notification to prescriber

Experimental group

Treatment:

Behavioral: New-prescription Alert with referral option

Behavioral: Existing-prescription notification to prescriber

New-prescription Alert/ Existing-prescription notification to pharmacist

Experimental group

Treatment:

Behavioral: Existing-prescription notification to pharmacist

Behavioral: New-prescription Alert

New-prescription Alert w/ referral option/ Existing-prescription notification to pharmacist

Experimental group

Treatment:

Behavioral: Existing-prescription notification to pharmacist

Behavioral: New-prescription Alert with referral option