Improved Ability to Cope With Everyday Life Through a Person-centered Training Program in Elderly Patients With Rheumatoid Arthritis - PEP-walk Study

Vastra Gotaland Region

Status: Completed

Conditions: Rheumatoid Arthritis

Treatments: Behavioral: Person-centered high-intense training under supervision; Behavioral: Personalized exercise program to perform at home

Study type: Interventional

Funder types: Other

Identifiers

NCT02397798

PEp-walk study

Details and patient eligibility

About

The purpose of this study is to examine whether person-centered high-intense aerobic / strength training during five months reduces inflammation and disease activity, improve immune cell function, and increases muscle strength, fitness and ability of the individual independence in elderly patients with rheumatoid arthritis.

Enrollment: 75 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion

• Patients 65 years or older with RA diagnosed according to the ACR / EULAR 1987/2010 criteria,
• disease duration 2 years or more,
• disease activity as measured by DAS28 <5.1

Exclusion

• Comorbidities, such as unstable coronary artery disease, uncontrolled cardiac arrhythmia, or uncontrolled high blood pressure, which prevents moderate to intense exercise.
• Joint surgery completed within 6 months prior to study entry.
• Ongoing training at moderate to high level 2 or more times per week

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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75 participants in 2 patient groups

Intervention

Experimental group

Description:

Person-centered high-intense training three times a week under supervision (supervision two times a week) during 5 months

Treatment:

Behavioral: Person-centered high-intense training under supervision

Control

Active Comparator group

Description:

Introduction to health-enhancing physical activity, personalized exercise program to perform at home three times a week during 5 months

Treatment:

Behavioral: Personalized exercise program to perform at home