Improved Medically Assisted Procreation Monitoring (NGAMP)

Rennes University Hospital

Status: Unknown

Conditions: Infertility

Treatments: Diagnostic Test: Dosage of oestradiol

Study type: Observational

Funder types: Other

Identifiers

NCT03274765

35RC15_3019

Details and patient eligibility

About

Patient care in Medically Assisted Procreation (MAP) requires a close and regular monitoring of the evolution of the estradiol rate. This monitoring allows the dose and duration of treatment to be accurately adjusted for each woman (every 24 or 48 hours) up to 10 to 15 days of treatment with gonadotrophins. Oestradiol (E2) is secreted by the growing ovarian follicles and reflects their growth and maturity. Its plasma dosage makes it possible to monitor the ovarian response to stimulation.

This monitoring involves several constraints amongst which disruption of work life, stress, fatigue that can alter the response to treatment

Full description

In order to improve the comfort of patients already under severe stress, simplification of this monitoring is proposed. The development of an immediate-release whole blood test for simplified monitoring of estradiol levels will provide considerable comfort in the management of patients. These patients are subjected to significant emotional and physical stress and the development of this test will reduce the negative consequences that result.

Enrollment: 30 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women over 18 years old
• Patient followed for monitoring of ovarian stimulation;
• Having received information on the protocol and given consent to participate

Exclusion criteria

• Adult under safeguard of justice, guardianship or curatorship
• Persons deprived of liberty.

Trial design

30 participants in 1 patient group

Women with ovarian stimulation

Description:

Women followed in the MAP center of the Rennes University Hospital for ovarian stimulation monitoring Dosage of oestradiol

Treatment:

Diagnostic Test: Dosage of oestradiol