Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

Kaohsiung Medical University

Status: Completed

Conditions: Injury to Nerve During Surgery

Treatments: Drug: sugammadex (Bridion)

Study type: Observational

Funder types: Other

Identifiers

NCT02314234

KMUH-IRB-20140248

Details and patient eligibility

About

To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Full description

Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• undergoing parotid surgery

Exclusion criteria

• facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease

Trial design

50 participants in 2 patient groups

Control group

Description:

did not receive muscle relaxant during anesthesia

Sugammadex group

Description:

received single dose of rocuronium for anesthesia and sugammadex at skin incision

Treatment:

Drug: sugammadex (Bridion)