Improvement of Migraine Severity and Frequency With Migraineguard ™

Herbacure Natural

Status: Completed

Conditions: Migraine; Headache

Treatments: Dietary Supplement: Migraineguard

Study type: Interventional

Funder types: Industry

Identifiers

NCT04759040

MIGRAINEGUARD

Details and patient eligibility

About

Numerous treatments have been recommended for the prevention of migraine. The purpose of this randomized double-blind placebo controlled trial was to assess the efficacy of MIGRAINEGUARD ™ supplement by Herbacure Natural containing a combination of COQ10 , magnesium, riboflavin ,feverfew , Skullcap and black pepper as prophylactic treatment for migraine.

Full description

Our team will assess MIGRAINEGUARD ™ , a migraine prevention supplement marketed Herbacure Natural for individual suffering from multiple migraine attacks in one month . The purpose of this 7-months , randomized, double-blind, placebo controlled study is to evaluate the efficacy and safety of MIGRAINEGUARD ™ produced by Herbacure Natural , A Canadian company based in Vancouver , BC , in reducing migraine headache severity and frequency of attacks compared to placebo when used every day, as a preventative solution for migraine and to assess and monitor the safety of its usage for adverse effects.

The primary end-point is the severity and the frequency reduction of migraine attacks. The secondary end-points will be the existence of adverse reaction.

Enrollment: 120 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult aged 18 to 65 years Female and Male
• Based on IHS criteria ,are diagnosed with migraine (criteria of the International Classification of Headaches Disorders)
• Individuals with minimum of 3 severe to extreme migraine attacks during the last 3 months .
• Generally in good health

Exclusion criteria

• Individuals taking any preventive treatment for migraine
• Excessive usage of painkillers
• Cancer & Head injury and trauma
• Any medical condition that may impact the validity of collected information
• Previous usage of Botox within 6 months of study
• Last week usage of triptans

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups, including a placebo group

MigraineGuard

Active Comparator group

Description:

Active supplement treatment , MigraineGuard capsule containing Coq10 , Magnesium ,Vit B2 , Skullcap Extract , Feverfew Extract , Piperine

Treatment:

Dietary Supplement: Migraineguard

Placebo for MigraineGuard

Placebo Comparator group

Description:

Placebo capsules non identifiable from Migraineguard capsules were used as control comparator

Treatment:

Dietary Supplement: Migraineguard