Improvement of the Etiological Diagnosis of the Pericarditis (PERICARDITE)

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Infective Pericarditis

Treatments: Biological: Nasal swab

Study type: Interventional

Funder types: Other

Identifiers

NCT02828085

2013-A00962-43 (Other Identifier)

2013-30

Details and patient eligibility

About

Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis. The etiologies are very numerous and can be classified as infectious, neoplastic, metabolic or systemic, toxic causes. Diagnosis is difficult, and 80% of etiologies remain classified idiopathic. In their laboratory to improve the diagnosis of this syndrome investigators have developed a strategy of systematic prescription of biological tests by kit. This prescription by 'kit' strategy proved its interest by comparison with an intuitive requirement of biological. In this study investigators want to improve the diagnostic causative of pericarditis by implementing a new diagnostic strategy. This new strategy includes (i) samples additional less invasive for the patient, the swab pharyngeal and nasal, (ii) the addition of at the outset of more effective diagnostic techniques: specific Polymerase Chain Reaction (PCR)

Enrollment: 979 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient prescribed with a pericarditis kit for etiological diagnosis of a pericardial syndrome.
• Adult patient (= or > 18 years old)
• Patient who freely signed the informed consent form.
• Patient affiliated to a health insurance regime

Exclusion criteria

• Minor patient ( age <18 years)
• Pregnant, parturient or breastfeeding woman
• Adult patient incapable or unable to consent
• Patient deprived of liberty under judgment
• Person living in a health or social specialised structure
• Person in vital emergency situation

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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979 participants in 1 patient group

Infective Pericarditis

Other group

Description:

In patient prescribed with a pericardite kit for an etiological diagnosis of a pericardial syndrome, an additional nasal swab will be performed in order to perform a specific diagnosis with PCR technique.

Treatment:

Biological: Nasal swab