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Improving Aspirin Prescription Rates in Outpatient Clinic

Cairo University (CU) logo

Cairo University (CU)

Status

Enrolling

Conditions

Small for Gestational Age (SGA)
Preeclampsia (PE)
Prevention &Amp; Control
Low Birth Weight

Treatments

Other: Aspirin prescription on outpatient basis

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Ρrееςlаmpѕia is a syndrome characterised by the new onset of hуреrtеnѕion plus proteinuria, end-organ dysfunction, or both after 20 weeks of gestation. It complicates 3-5% of pregnancies.

Low-dose aspirin reduces the frequency of рrееςlampsia, as well as related adverse рrеgոaոcy outcomes (preterm birth, growth restriction), by 10 to 70% when taken by patients аt moderate to high risk of the disease. It has an excellent maternal/fetal safety profile. Thus, it is a reasonable preventive strategy for these patients.

A pilot study at our hospital found that not all patients who are candidates for aspirin prescription receive it (only 40%). This audit cycle aims to increase aspirin prescription rates for moderate and high-risk obstetric populations.

Enrollment

300 estimated patients

Sex

Female

Volunteers

No Healthy Volunteers

Inclusion criteria

Women at high risk are those with any of the following:

  1. hypertensive disease during a previous pregnancy
  2. chronic kidney disease
  3. autoimmune disease such as systemic lupus erythematosus or antiphospholipid syndrome
  4. type 1 or type 2 diabetes
  5. chronic hypertension.

Women with more than one moderate risk factor, such as are:

  1. nulliparity
  2. age 40 years or older
  3. pregnancy interval of more than 10 years
  4. body mass index (BMI) of 35 kg/m2 or more at first visit
  5. family history of pre-eclampsia
  6. multi-fetal pregnancy.

Exclusion criteria

  • None. All eligible candidates will be included.

Trial design

300 participants in 1 patient group

Obstetric population candidate for aspirin prescription
Description:
Moderate- and high-risk obstetric population
Treatment:
Other: Aspirin prescription on outpatient basis

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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