Improving Cardiac Secondary Prevention

Western University, Canada

Status: Active, not recruiting

Conditions: Myocardial Infarction; Secondary Prevention

Treatments: Behavioral: Education regarding telomere length

Study type: Interventional

Funder types: Other

Identifiers

NCT03269708

109209

Details and patient eligibility

About

The purpose of this study is to determine whether providing individuals with personalized information on cellular aging, including telomere length, will stimulate them to adhere to cardiac prevention strategies and improve exercise capacity.

Full description

Individuals who have sustained a heart attack are at considerable risk for future cardiac events. A cardiac rehabilitation and exercise program can reduce this risk but it remains a challenge to adopt optimum lifestyle changes. We will determine whether providing individuals with information on leukocyte telomere length, will motivate them to improve their exercise performance. We will test whether professionally conveying this information will stimulate an individual to adhere to proven cardiac prevention strategies, looking at the extent to which one's exercise capacity improves over time.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Individuals who have sustained a myocardial infarction and entered the cardiac rehabilitation program

Exclusion criteria

1. Individuals with genetic mutations that affect telomere length
2. Individuals who may not have the mental capacity to understanding the ramifications of risk biomarkers

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

Control

No Intervention group

Description:

Participants receive standard care in cardiac rehabilitation program

Knowledge transfer group

Experimental group

Description:

Participants receive standard care in cardiac rehabilitation program plus education regarding telomere length

Treatment:

Behavioral: Education regarding telomere length