Improving Clinical PET/CT Image Quality in Retrospectively Reconstructed Breath-Hold Images

Memorial Sloan Kettering Cancer Center (MSK)

Status: Terminated

Conditions: Lung Cancer

Treatments: Other: Breath-Hold PET/CT image set

Study type: Observational

Funder types: Other

Identifiers

NCT01109953

10-054

Details and patient eligibility

About

The patient has been referred for an FDG PET/CT scan. FDG is a form of sugar that contains a small amount of radioactivity; it is used to see the size and possible spread of cancer in the body.

Pictures of the body are taken on a machine called a PET/CT scanner. The purpose of this current study is to see if we, the investigators, can take clearer pictures of the tumor than we could with our routine scan method. This would allow us to better see how FDG is picked up by the tumor. PET/CT is presently one of the best tools for detecting cancer and determining its spread in the body. However, due to breathing motion, PET and CT images may become blurred and the location of the tumor on CT and PET images may not match. We have developed a new method that enables us to reduce image blurring and to measure the tumor more accurately on PET images. In this study we want to compare two kinds of images: those from the standard PET/CT scan, and the PET/CT scan pictures taken with our new method.

If successful, we may use this new method for clinical routine in the future.

Enrollment: 6 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participant is capable of providing written consent.
• 18 years of age or older.
• Patient with a known or suspected FDG-avid malignancy in the torso

Exclusion criteria

• none

Trial design

6 participants in 1 patient group

Breath-Hold PET/CT image

Description:

In addition to the standard clinical PET/CT images, we will provide a breath-hold PET/CT image set, using the same PET data for both.

Treatment:

Other: Breath-Hold PET/CT image set