Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?

St. Olavs Hospital

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Strength training and treadmill training

Study type: Interventional

Funder types: Other

Identifiers

NCT01074827

09/225

Details and patient eligibility

About

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

Enrollment: 28 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with Multiple Sclerosis,classified as relapsing remitting,or primary/secondary progressive
• Expanded Disability Status Scale (EDSS)score of ≤ 6
• Reduced walking ability (subjectively experienced)

Exclusion criteria

• persons with a level of ataxia, clinically assessed, that would affect their ability to perform the training.
• spasticity requiring stretching og treatment with baclofen.
• Other, not MS-related, conditions affecting walking ability.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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28 participants in 2 patient groups

Treadmill group

Experimental group

Description:

Specific gait training on treadmill

Treatment:

Other: Strength training and treadmill training

Strength training group

Experimental group

Description:

Eight weeks of intensive strength training

Treatment:

Other: Strength training and treadmill training