Improving Human Ovarian Transplantation

Hadassah Medical Center

Status and phase: Unknown; Early Phase 1

Conditions: Fertility Preservation

Treatments: Procedure: ovarian transplantation

Study type: Interventional

Funder types: Other

Identifiers

NCT00827476

0530-08-HMO- CTIL

Details and patient eligibility

About

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.

Full description

Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.

Enrollment: 100 estimated patients

Sex: Female

Ages: 5 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• tissue previously obtained

Exclusion criteria

• no tissue available or no consent

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

100 participants in 1 patient group

ovarian transplantation

Experimental group

Description:

tissue will be used for xenotransplantation or in vitro culture

Treatment:

Procedure: ovarian transplantation