Improving Outcomes of Respiratory Patients With Exertional Hypoxemia

Changi General Hospital

Status: Enrolling

Conditions: Pulmonary Rehabilitation

Treatments: Device: High flow oxygen; Other: Usual care

Study type: Interventional

Funder types: Other

Identifiers

NCT05752370

2022/2605

Details and patient eligibility

About

The primary aim of this pilot randomized controlled trial is to determine feasibility of the proposed pulmonary rehabilitation intervention.

Full description

In this pilot randomized controlled trial, our primary aim is to determine feasibility of the proposed intervention.

Enrollment: 56 estimated patients

Sex: All

Ages: 21 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 21 years and above
• Presence of exertional hypoxemia during 1-minute sit-to-stand test
• diagnosis of acute COPD exacerbation or Covid-19 pneumonia or exacerbation of bronchiectasis or exacerbation of interstitial lung disease
• physically fit to participate in exercise therapy as determined by both the patient's physician and physiotherapist

Exclusion criteria

• uncontrolled severe medical conditions
• currently enrolled in a pulmonary rehabilitation trial
• unsuitable for randomization as determined by the patient's physician

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

56 participants in 2 patient groups

High flow oxygen

Experimental group

Description:

High flow nasal oxygen

Treatment:

Device: High flow oxygen

Usual care

Active Comparator group

Description:

room air or normal flow oxygen

Treatment:

Other: Usual care