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Improving Patient Access to Stroke Therapy Study (IMPACT)

Medical College of Wisconsin logo

Medical College of Wisconsin

Status

Terminated

Conditions

Ischemic Stroke
Transient Ischemic Attack

Treatments

Device: Endovascular therapy
Drug: Activase

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Limited access is a major hurdle in the treatment of AIS; many hospitals, especially rural hospitals, do not have the infrastructure or medical support to effectively treat AIS patients.5 Failure to recognize the signs and symptoms of stroke by the patient and/or emergency medical services (EMS) is another barrier to the timely treatment of AIS. Several studies, including the Paul Coverdell National Acute Stroke Registry (PCNASR), have reported low rates of adherence to stroke care guidelines, suggesting that many AIS patients do not receive proper treatment according to established guidelines. Thus, there remains an increasing need to assess and address the barriers that prevent patient access to proper AIS treatment.

Annually, approximately 20,000 patients are discharged from Wisconsin hospitals with the diagnosis of stroke and an estimated 4,000 patients die from stroke each year in WI. To date, there have been no statewide studies initiated in Wisconsin to assess the regional barriers to the treatment of AIS patients with thrombolytic or endovascular therapy, and many hospitals do not routinely collect and analyze AIS patient data.

The goal of the Improving Patient Access to Stroke Therapy (IMPACT) pilot study is to engage community hospitals statewide to identify the regional barriers to AIS therapy in WI.

Enrollment

500 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age > 18 years
  • Clinical diagnosis of acute ischemic stroke or transient ischemic attack (TIA)
  • ICD-9-CM code indicative of stroke or TIA

Exclusion criteria

  • Clinical diagnosis of intracerebral hemorrhage or subarachnoid hemorrhage
  • Stroke or TIA occurred while patient was hospitalized

Trial design

500 participants in 1 patient group

Acute ischemic stroke or TIA
Description:
Patients presenting with acute ischemic stroke or transient ischemic attack and underwent treatment using Activase and/or endovascular therapy.
Treatment:
Drug: Activase
Device: Endovascular therapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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