Improving Reproductive Function in Women With Polycystic Ovary Syndrome by High Intensity Interval Training (IMPROV-IT)

Norwegian University of Science and Technology

Status: Completed

Conditions: Polycystic Ovary Syndrome

Treatments: Behavioral: 10x1 minute high intensity interval training; Behavioral: 4x4 minutes high intensity interval training

Study type: Interventional

Funder types: Other

Identifiers

NCT02419482

2015/468

Details and patient eligibility

About

The aim is to investigate whether 16 weeks of high intensity interval training, followed by 36 weeks of home-based exercise, will improve menstrual frequency in women with Polycystic Ovary Syndrome (PCOS) compared with a non-exercising control group.

Enrollment: 64 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Polycystic ovary syndrome (PCOS) according to the Rotterdam criteria

Exclusion criteria

• Regular high intensity endurance (two or more times per week of vigorous exercise).
• Concurrent treatments (insulin sensitizers or drugs known to affect gonadotropin or ovulation, with a wash out period of 1 months prior to inclusion).
• On-going pregnancy.
• Breast feeding within 24 weeks
• Cardiovascular disease or endocrine disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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64 participants in 3 patient groups

4x4 minutes interval training

Experimental group

Description:

4x4 minutes high intensity interval training with 4 minute intervals

Treatment:

Behavioral: 4x4 minutes high intensity interval training

10x1 minute interval training

Experimental group

Description:

10x1 minute high intensity interval training with 1 minute intervals

Treatment:

Behavioral: 10x1 minute high intensity interval training

control

No Intervention group

Description:

Physical activity recommended