Improving Sensitivity of Urine Cytology for Bladder Cancer

Johns Hopkins University

Status: Withdrawn

Conditions: Bladder Cancer

Treatments: Device: La-Z-Boy Massage Chair Vibration Effect on Bladder Cancer Cell Concentration

Study type: Interventional

Funder types: Other

Identifiers

NCT01826097

NA_00067544

Details and patient eligibility

About

Can a commercially available vibrating chair increase the number of urothelial cells in a urine sample of healthy participants non-invasively? The investigators plan is participants will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in the vibrating chair for one hour. The control group will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in a non-vibrating chair for one hour. Then, urine samples will be collected and examined for urothelial cell concentration for both groups.

Sex: Male

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Only adult male subjects who will not have surgery within a period of 2 weeks.
• Over the age of 18
• Have had a confirmed diagnosis of stage 0-4 transitional cell carcinoma within the last 30 days

Exclusion criteria

• Cognitive impairment resulting in the inability to give informed consent
• Lack of spoken and written English resulting in the inability to give informed consent
• Presence of infectious disease
• Insulin dependent diabetes mellitus
• Endogenous osteosynthetical material implants
• Knee or hip prosthesis
• Pacemaker
• Epilepsy
• Musculo-skeletal disorders
• Weight in excess of 250 pounds
• Poor circulation

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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0 participants in 1 patient group

Vibration

Experimental group

Description:

Whole body vibration applied to a group of 20 bladder cancer patients.

Treatment:

Device: La-Z-Boy Massage Chair Vibration Effect on Bladder Cancer Cell Concentration