Improving Tolerability of Bowel Preparation Laxative for Colonoscopy

Howard University

Status: Completed

Conditions: Bowel Preparation; Colonoscopy

Treatments: Other: Pattern of flavoring of bowel laxative

Study type: Interventional

Funder types: Other

Identifiers

NCT02062112

IRB-13-MED-60

Details and patient eligibility

About

The purpose of this study is to determine whether the pattern of flavoring and drinking of laxatives for colonoscopy can improve the experience of patients when they are undergoing bowel preparation for the test.

Investigators hypothesize that patients will have a better experience if patients taste the bowel preparation laxative with and without flavoring and then decide how they want to drink the rest of the laxative since taste preferences vary widely from person to person.

Enrollment: 313 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (18 years and older) referred for outpatient colonoscopy

Exclusion criteria

• Patients with history of bowel resection
• patients with history of inflammatory bowel disease
• History of polyposis syndrome
• History of colorectal cancer
• History of poor taste perception from any cause

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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313 participants in 3 patient groups

Unflavored group

No Intervention group

Description:

The patient will mix 1 gallon of polyethylene glycol with water and drink as directed by his/her endoscopist. No flavoring will be added.

Flavored group

Active Comparator group

Description:

The patient will mix 1 gallon of polyethylene glycol with water, add flavoring to the entire solution and drink at the time specified by his/her endoscopist.

Treatment:

Other: Pattern of flavoring of bowel laxative

Liberal group

Active Comparator group

Description:

The patient will mix 1 gallon of polyethylene glycol with water. Fill 2 cups with the solution. The patient will add flavoring to one cup and drink both the flavored and unflavored solutions in the cups. The patient will then determine how he/she wants to drink the rest of the bowel preparation laxatives based on their taste preference and drink at the time specified by his/her endoscopist.

Treatment:

Other: Pattern of flavoring of bowel laxative