Improving Weight Loss Outcomes for Binge Eating Disorder.

Drexel University

Status: Completed

Conditions: Weight Loss; Binge-Eating Disorder; Eating Disorder; Binge Eating

Treatments: Behavioral: Standard Behavior Therapy; Behavioral: Acceptance-Based Behavioral Weight Loss Therapy for BED

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03712462

R01DK117072 (U.S. NIH Grant/Contract)

1803006178

Details and patient eligibility

About

This study aims to develop and evaluate the efficacy of a behavioral weight loss treatment approach for individuals with binge eating disorder to both reduce their binge eating behaviors and lose weight.

Full description

In the current study, we propose to (a) compare the efficacy of an acceptance-based behavioral treatment (ABBT) that targets both binge eating and weight loss in patients with binge eating disorder (BED) to a Standard Behavioral Weight Loss Treatment (SBT), (b) evaluate the extent to which ABBT and SBT target shared maintenance factors for binge eating and overeating episodes, and (c) assess whether treatment efficacy is moderated by baseline values of constructs targeted in ABBT. Our study will be the first to evaluate an ABBT for BED designed to 1) address maintenance factors that give rise to both binge eating episodes and overeating episodes without loss of control and 2) increase adherence to BWL prescriptions.

Enrollment: 126 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meet the DSM-5 criteria for Binge Eating Disorder
• Have a BMI range of 27-50kg/m2

Exclusion criteria

• are unable to fluently speak, write, and read English
• are currently experiencing severe psychopathology that would limit their ability to engage in study (e.g., suicidality, substance use disorder, psychotic disorder)
• are unable to engage in moderate physical activity (i.e., walk 2 blocks without rest)
• have a medical condition (e.g., acute coronary syndrome, type I diabetes) that would pose a risk to the participant during intervention, cause a change in weight, or limit ability to comply with the recommendations of the program
• Pregnant or planning to become pregnant in the next 2 years
• Recently began a course of or changed the dosage of medication that can cause significant change in weight
• Have a history of bariatric surgery
• Have had weight loss of > 5% in the past 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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126 participants in 2 patient groups

ABBT Weight Loss Therapy for BED

Experimental group

Description:

Acceptance-Based Behavioral Weight Loss Therapy for BED

Treatment:

Behavioral: Acceptance-Based Behavioral Weight Loss Therapy for BED

Standard Behavior Therapy

Active Comparator group

Description:

Standard Behavioral Weight Loss Therapy

Treatment:

Behavioral: Standard Behavior Therapy