Improving Work Outcome for People With Severe Mental Illness

Mental Health Services in the Capital Region, Denmark

Status: Completed

Conditions: Bipolar Affective Disorder; Recurrent Depressive Disorder; Schizophrenia, Schizotypal and Delusional Disorders

Treatments: Behavioral: IPS plus; Behavioral: Individual Placement and support (IPS)

Study type: Interventional

Funder types: Other

Identifiers

NCT01722344

PCK-2012-CT-2912

Details and patient eligibility

About

The purpose of this study is to investigate the efficacy of IPS in Denmark and compare effects of 1. Individual Placement and Support (IPS) vs. 2. IPS + cognitive remediation and work-related social skills training vs. 3. standard intervention, among individuals with severe mental illness.

Full description

Individual Placement and Support (IPS) is established as the most effective vocational intervention available for persons with severe mental illness,and the intervention is widely recognized as an evidence-based practice. Despite evidence, long-term job retention and economic self-sufficiency have not been clearly demonstrated. Research has suggested that integrating methods such as cognitive remediation and social skills training could reduce such limitations. Further, there has not been conducted any randomized controled trials with IPS in Scandinavian countries with highly developed and generous social security and welfare systems, and with high thresholds to the open labour market.

The aim of this study is to investigate the effectiveness of IPS in Denmark and compare effects of 1. IPS vs. 2. IPS + cognitive remediation and work-related social skills training vs. 3. Standard intervention.

The intervention is based on the 7 principles of IPS Supported Employment, and IPS enhanced with cognitive remediation and work-related social skills training, consists of 24 sessions of computer based cognitive training and 24 group based sessions of cognitive coping strategies and work-related social skills training.

Enrollment: 717 patients

Sex: All

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Psychosis within the schizophrenic spectrum (F 2, International Classification of Diseases (ICD 10)).

Severe depression (F33, ICD-10) or Bipolar disorder (F31, ICD-10) and minimum 3 years psychiatric treatment.

Motivated for employment or education. 18 to 65 years old. Participants must speak and understand Danish.

Exclusion criteria

Lack of informed consent Above 64 years and receiving state pension Match group 1 (No problems besides unemployment)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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717 participants in 3 patient groups

Individual Placement and Support (IPS)

Experimental group

Treatment:

Behavioral: Individual Placement and support (IPS)

IPS plus

Experimental group

Description:

Individual Placement and Support plus cognitive remediation and work-related social skills training

Treatment:

Behavioral: Individual Placement and support (IPS)

Behavioral: IPS plus

Standard intervention

No Intervention group