IMRT Lower Limb Soft Tissue Sarcoma

University Health Network, Toronto

Status and phase: Completed; Phase 2

Conditions: Sarcoma

Treatments: Radiation: Intensity Modulated Radiation Therapy

Study type: Interventional

Funder types: Other; NETWORK

Identifiers

NCT00188175

UHN REB 03-0107-C

Details and patient eligibility

About

Intensity-modulated radiation therapy may make wound healing problems less likely by 1)precisely shaping the region of high radiation dose to the shape of the tissue which harbours tumour cells, and 2) precisely shaping the regions of low radiation dose to the shapes of the normal tissues which are more sensitive to radiation effects.

Enrollment: 59 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically proven soft tissue sarcoma
• Lesion lies between the iliac crest (hipbone) and the ankle
• Lesion is newly diagnosed
• Assessed by radiation oncologist and surgical oncologist

Exclusion criteria

• Benign histologies
• Histologies generally treated with chemotherapy
• Prior or recurrent cancer, except nonmelanomatous skin cancer or carcinoma in-situ of the cervix

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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59 participants in 1 patient group

IMRT for lower limb soft tissue sarcoma

Experimental group

Treatment:

Radiation: Intensity Modulated Radiation Therapy