IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms (MOTOR-CHILD)

Istituto Ortopedico Rizzoli

Status: Completed

Conditions: Valgus, Talipes; Hyperlordosis; Varus; Talipes; Hyperkyphosis; Genu Varum; Cavus Foot; Scoliosis Idiopathic; Genu Valgus; Laxity of Ligament; Angular Limb Deformity; Flat Feet

Treatments: Diagnostic Test: Clinical tests and motor control evaluation using Inertial Measurement Units

Study type: Interventional

Funder types: Other

Identifiers

NCT05763901

0004188

Details and patient eligibility

About

While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether conditions much more frequent in the pediatric population, the so-called "Paramorphisms or Dysmorphisms", may be associated with more or less noticeable changes in locomotor development.

On a few studies, flat feet and hyperlaxity has been correlated with a motor control delay or poorer motor performance, based on complex clinical tests or on stereophotogrammetry movement analysis.

Although promising, these preliminary studies, in addition to not providing information on the possible influence of other paramorphisms, such as varus and valgus of the knees, do not provide conclusive indications.

The aim of this study is to investigate, through clinical tests and wearable inertial units, the motor control of a pediatric population affected by Paramorphisms or Dysmorphisms and to compare them with a population of healthy controls, matched by age, taken from the recently developed control data set from Bisi and Stagni.

Enrollment: 151 patients

Sex: All

Ages: 6 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Born at term
• Without known delay in motor development
• Finding of one or more paramorphisms or dysmorphisms of the developmental age (flat or cavus foot, valgus or varus talipes, valgus or varus knee, scoliotic attitude or scoliosis, hyperkyphosis or hyperlordosis, generalized or focused hyperlaxity, heterometry of the AAII, torsional defects AAII)

Exclusion criteria

• Preterm birth
• Diagnosis of pathologies compromising motor control (Infantile Cerebral Palsy, Neuromuscular Diseases, Spina Bifida, Arthrogryposis, Genetic Syndromes)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

151 participants in 1 patient group

Paramorphisms/dysmorphisms of spine and/or lower limbs

Experimental group

Description:

Only one arm of patients assessed for motor competence and balance without controls

Treatment:

Diagnostic Test: Clinical tests and motor control evaluation using Inertial Measurement Units