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In-depth ECG Analysis for the Extraction of Biomarkers of Cardiac Mechanical Dispersion (AFICIONADO)

C

Central Hospital, Nancy, France

Status

Not yet enrolling

Conditions

Cardiovascular Pathology

Treatments

Device: Echocardiography
Device: ECG

Study type

Observational

Funder types

Other

Identifiers

NCT06163911
2023PI117

Details and patient eligibility

About

Left ventricular systolic dysfunction (LVSD) refers to impaired contraction of the left ventricle, and can lead to heart failure and death. Early identification of LVSD, which often remains asymptomatic for years, is therefore crucial to mitigate the associated risks through appropriate treatment. Echocardiographic screening of asymptomatic individuals is costly, requires access to experts, and the criteria for selecting potential high-risk individuals for screening remain unclear.

Unlike echocardiography, the electrocardiogram (ECG) is a relatively low-cost procedure, routinely available and requiring little technical training to set up the examination and collect data, making it an interesting tool for early detection of LVSD.

Enrollment

100 estimated patients

Sex

All

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Person who has received full information on the organization of the research and has not objected to the use of this data;
  • Age ≥ 50;
  • Persons who have undergone an echocardiographic examination and a 12-lead ECG examination during consultations at the CHRU de Nancy;
  • Persons with at least one cardiovascular risk (obesity, diabetes, hypertension, etc.).

Exclusion criteria

  • People with a history of heart disease (ischemic, valvular);
  • Patients with significant 12-lead ECG abnormalities (complete bundle branch block, sequelae of myocardial infarction, etc.);
  • ECG tracings or echocardiograms that cannot be analyzed.

Trial design

100 participants in 2 patient groups

No myocardial contractility abnormalities
Treatment:
Device: Echocardiography
Device: ECG
Myocardial contractility abnormalities
Treatment:
Device: Echocardiography
Device: ECG

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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