In-Hospital Detection of Elevated Blood Pressure (INDEBP)

Annina Vischer

Status: Enrolling

Conditions: Blood Pressure, High; Hypertension

Treatments: Other: Postponement of antihypertensive treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT06132451

INDEBP-prospective

2023-01566 (Other Identifier)

Details and patient eligibility

About

The goal of this clinical trial is to analyse the prevalence of new or uncontrolled arterial hypertension (AHT) after hospital discharge of medical in-patients with elevated blood pressure (BP) values during hospitalisation.

The main questions it aims to answer are:

• Do elevated BP values during hospitalisation correspond to new or uncontrolled AHT after hospital discharge?
• Is it safe to postpone adaption of antihypertensive treatment until after proper evaluation of AHT after hospital discharge?

Participants will either be treated according to their physicians' decision or antihypertensive treatment adaptions will be postponed until after hospital discharge.

Enrollment: 800 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient hospitalized on the internal medicine ward for non-cardiovascular causes, i.e. patients hospitalized for conditions, which are not acutely worsened by uncontrolled AHT
• Asymptomatic elevated BP values (defined as 140-180 mmHg systolic and/or 90-110 mmHg diastolic) on at least 2 occasions
• Ability to understand study procedures and to provide written informed consent

Exclusion criteria

• Hospitalization for any conditions which can be worsened by uncontrolled AHT:
• Cerebrovascular events
• Acute coronary syndrome
• Acute or decompensated heart failure
• Any condition preventing ABPM
• Pregnant or lactating women
• Failure to provide informed consent

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

800 participants in 2 patient groups

Usual practice arm

No Intervention group

Description:

Patients will be treated according to their treating physicians' decision.

Postponement of treatment arm

Other group

Description:

Antihypertensive treatment adaptions will be postponed until after a 24h ambulatory blood pressure measurement (ABPM) 4 weeks after hospital discharge.

Treatment:

Other: Postponement of antihypertensive treatment