In-utero Death and Birth Mortality in Reunion Island (RAMIR)

Centre Hospitalier Universitaire de la Réunion

Status: Terminated

Conditions: Infant Death; Pregnancy Loss

Treatments: Other: Birth control for foetal death; Other: Birth control for new-born death; Other: Foetal death; Other: New-born death

Study type: Observational

Funder types: Other

Identifiers

NCT03354832

2016/CHU/08

Details and patient eligibility

About

Infant mortality is still relevant despite the improvement and the accessibility of hospital care. Premature birth are two fold higher than in metropolitan France. Some factors has been suspected such as precariousness, alcoholism, congenital malformation, care accessibility, epidemic environment ... Nevertheless, the impact of these factors on foetal death or new-born death are not yet sufficiently quantified to provide appropriate care and prevention action in Reunion Island.

Full description

Through the analysis of interview of the mothers that have lost their infant during pregnancy or just after birth, the study aims to draw a picture of the pregnancy cares offer and pregnancy conditions in Reunion Island.

This study is an non interventional case-control study. Socio-economic conditions, pregnancy care and prevention are screened to identified the major cause of foetal or new-born death in Reunion Island. These data are still lacking and will be useful to identify which public health actions that should be organized.

Enrollment: 45 patients

Sex: Female

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Case: foetal death (foetus weighing more than 500 g or more than 22-amenorrhea weeks old) or new-born death (premature: more than 23-amenorrhea weeks old or mature)
• Control: premature (more than 23-amenorrhea weeks old) or mature new-born, alive when the leave the hospital

Exclusion criteria

• medical abortion
• second pregnancy during the study period
• case under forensic expertise

Trial design

45 participants in 4 patient groups

Foetal death

Description:

In-utero dead foetus weighting at least 500 g or 22-amenorrhea weeks old. In utero death means that death occurs during delivery or per partum

Treatment:

Other: Foetal death

New-born death

Description:

New-born dead during post-birth hospital stay and at least 23-amenorrhea weeks old.

Treatment:

Other: New-born death

Birth control for foetal death

Description:

Same gender child born, and alive, in the same hospital, and born on time (37-41 amenorrhea weeks old).

Treatment:

Other: Birth control for foetal death

Birth control for new-born death

Description:

Same gender infant born, and alive, in the same hospital, and: * for 23-amenorrhea weeks old new-born death: control new-born are born on time (37-41 amenorrhea weeks old). * for 24 to 31-amenorrhea weeks old new-born death: control new-born are premature infant (24-31 amenorrhea weeks old), and are included when their hospital stay ends. * for 32 and more-amenorrhea weeks old new-born death: control new-born are 32 and more-amenorrhea weeks old infant

Treatment:

Other: Birth control for new-born death