In Vitro Maturation of Immature Oocytes

Sheba Medical Center

Status: Completed

Conditions: Ovarian Hyperstimulation Syndrome; Polycystic Ovary Syndrome

Treatments: Procedure: In Vitro Maturation of immature oocytes

Study type: Interventional

Funder types: Other

Identifiers

NCT00480337

SHEBA-06-4317-AH-CTIL

Details and patient eligibility

About

The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as performed during normal IVF.We will record the efficacy and safety of this procedure.

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women with PCOS
• Women with previous Hyperstimulation or with risk of developing hyperstimulation during IVF Treatment
• Women diagnosed with cancer who are interested in fertility preservation
• Women with repeated IVF failure

Exclusion criteria

• Severe cases of endometriosis
• Large myomas
• Hydrosalpinxs Technical problem with previous oocytes pick-up

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)