In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization (IVM vs IVF)

Batzofin Fertility Services

Status: Suspended

Conditions: Infertility

Treatments: Procedure: In vitro maturation and in vitro fertilization; Procedure: Low doses of gonadotropin stimulation.

Study type: Interventional

Funder types: Other

Identifiers

NCT00867763

2939

Details and patient eligibility

About

Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation doses. The goal of the research is to determine which of these if more suitable as a low cost approach for varying individual patients.

Full description

Low cost environment is utilized, but fees are charged.

Enrollment: 1,440 estimated patients

Sex: Female

Ages: 21 to 41 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Under age 42 female, normal uterine cavity, BMI 18-34kg/m2,

Exclusion criteria

• Donor eggs, donor sperm, myoma over 5 cm
• Current hydrosalpinx, abnormal uterine cavity.

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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1,440 participants in 2 patient groups

IVM

Experimental group

Description:

Early egg retrieval, in vitro maturation, then IVF

Treatment:

Procedure: In vitro maturation and in vitro fertilization

Mild IVF

Active Comparator group

Description:

Mild gonadotropin and conventional IVF

Treatment:

Procedure: Low doses of gonadotropin stimulation.