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In Vitro Models of Liver and Pancreatic Cancer

NHS Foundation Trust logo

NHS Foundation Trust

Status

Unknown

Conditions

Hepatocellular Carcinoma
Cholangiocarcinoma
Pancreatic Neoplasm

Treatments

Genetic: Organoid in vitro culture

Study type

Observational

Funder types

Other

Identifiers

NCT02436564
A093484

Details and patient eligibility

About

The primary objective is to develop an in vitro model of cancer for laboratory study using liver, biliary and pancreatic cancer tissue. The secondary objective is to study the genetic and cellular biology of cancer of the liver, biliary tract and the pancreas. As well the investigators hope to compare molecular and cellular biology of cancer cells with normal cells as well as potentially test the efficacy of current and future anti-cancer therapies.

Samples will be collected from tissue that has been resected as part of the treatment for a patient diagnosed with liver, bile duct or pancreas cancer.

Enrollment

75 estimated patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All adult patients undergoing surgical resections for liver, biliary or pancreas cancers that are able to give informed consent.

Exclusion criteria

  • Patients aged <18 or those who are unable to give informed consent.

Trial contacts and locations

1

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Central trial contact

Nikitas Georgakopoulos, BSc; Kourosh Saeb-Parsy, PhD, FRCS

Data sourced from clinicaltrials.gov

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